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200729400 - Control of BKD by Inactivation of the Renibacterium salmoninarum Sortase Enzyme as an Alternative to Antibiotics

Sponsor: Northwest Fisheries Science Center

Budgets: FY07: $223,694 | FY08: $238,875 | FY09: $251,359

Short description: This proposal describes research to determine if the sortase gene product of Renibacterium salmoninarum can be a target for therapeutic drugs against Bacterial Kidney Disease of salmon.

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Final Council recommendation (Nov 2006)

Funding category: Expense

Recommended budgets: FY07: $0 | FY08: $0 | FY09: $0


ISRP final recommendation: Fundable


This is an excellent proposal, with excellent technical and scientific background. Potential benefits to fish are clear. In reality, many hatchery operations (and the populations they impact) could be affected positively. Project proponents have a good track record of peer reviewed publications and participation in fisheries meetings. Results of the work could have significant and lasting benefits to the artificial production programs, including reducing the impact and risks of these programs to natural fish populations.

State/province recommendation: MS: Recommended Action

Review group: MSRT

Recommended budgets: FY07: (n/a) | FY08: (n/a) | FY09: (n/a)

Comment: This project addresses a High Priority issue within the basin hatcheries. It is unclear to the MSRT if this project is the one to address this issue. The ISRP review should help in the final determination of technical merits for this project. This proposal should be reviewed with all hatchery reform or hatchery research projects.